The Urocortin Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to UCN, and Urocortin. This antibody recognizes Human, Mouse, and Rat antigen. The Urocortin Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
Function: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563). Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity).
Subunit Structure: Interacts with CRHR1 and CRHR2 (via their N-terminal extracellular domain).
Similarity: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family